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Acta Neurochir (Wien). 2012 May;154(5):823-30. doi: 10.1007/s00701-012-1306-4. Epub 2012 Feb 27.

The long-term surgical outcomes of secondary hemidystonia associated with post-traumatic brain injury.

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1
Department of Neurosurgery, Severance Hospital, Brain Korea 21 Project for Medical Science, Brain Research Institute, Yonsei University College of Medicine, Seodaemun-Gu, Seoul, Republic of Korea.

Abstract

BACKGROUND:

The aim was to assess the effect of deep brain stimulation for secondary hemidystonias associated with focal post-traumatic brain injuries.

METHODS:

Four patients underwent deep brain stimulation for the treatment of medically refractory secondary hemidystonia associated with post-traumatic brain injury. Clinical outcome assessments were based on Burke-Fahn-Marsden Dystonia Rating Scale movement and disability scores. Health-related quality of life was assessed using a 36-item short-form general health survey questionnaire administered preoperatively and at the last follow-up visit.

RESULTS:

Burke-Fahn-Marsden Dystonia Rating Scale movement scores had improved by 73.2% (range, 38.1-94.1) and disability scores had improved by 75% (range, 60-100) at the 2-year follow-up visit. The health-related quality of life assessment revealed satisfactory results at follow-up, such that body pain, general health, vitality, social functioning, as well as emotional and mental health improved significantly.

CONCLUSIONS:

Globus pallidus internus deep brain stimulation can be used to modulate and ameliorate secondary hemidystonia associated with focal post-traumatic brain injury.

PMID:
22367408
DOI:
10.1007/s00701-012-1306-4
[Indexed for MEDLINE]
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