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Pediatr Nephrol. 2012 Nov;27(11):2007-16. doi: 10.1007/s00467-011-2080-x. Epub 2012 Feb 28.

Continuous renal replacement therapy in children.

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1
Department of Pediatrics, Division of Nephrology, Stanford University Medical Center, 300 Pasteur Drive, Room G-306, Stanford, CA 94035, USA. suthersm@stanford.edu

Abstract

Over the past several decades, the epidemiology of acute kidney injury (AKI) in children has changed significantly. Pediatric patients with AKI frequently have co-morbid conditions, substantial fluid overload, and marked disease severity. At the same time, continuous renal replacement therapy (CRRT) has become the preferred modality for the management of these patients. This manuscript provides a state-of-the-art review of the technical aspects of pediatric CRRT and examines the most recent data regarding CRRT indications, timing of initiation, dosing, and outcomes in critically ill children.

PMID:
22366896
DOI:
10.1007/s00467-011-2080-x
[Indexed for MEDLINE]
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