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Clin Chest Med. 2012 Mar;33(1):151-63. doi: 10.1016/j.ccm.2011.12.004. Epub 2012 Jan 24.

Chronic hypersensitivity pneumonitis.

Author information

1
Department of Pneumology/Allergy, Ruhrlandklinik, University Hospital, Essen, Germany. ulrich.costabel@ruhrlandklinik.uk-essen.de

Abstract

Hypersensitivity pneumonitis (HP) is a complex syndrome caused by the inhalation of environmental antigens. Chronic HP may mimic other fibrotic lung diseases, such as idiopathic pulmonary fibrosis. Recognition of the antigen is important for diagnosis; avoidance of further exposure is critical for treatment. Fibrosis on biopsy or high-resolution computed tomography is a predictor of increased mortality. Additional research is needed to understand why the disease develops only in a minority of exposed individuals and why cases of chronic HP may progress without further antigen exposure.

PMID:
22365252
DOI:
10.1016/j.ccm.2011.12.004
[Indexed for MEDLINE]

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