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Curr Biol. 2012 Feb 21;22(4):R137-9. doi: 10.1016/j.cub.2012.01.002.

Wnt signaling: the many interfaces of β-catenin.

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1
Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Abstract

Wnt signaling regulates virtually every cell fate decision during development. How can the same signal trigger such diverse events? Engaging different transcriptional machinery via different protein interfaces on the transcriptional co-activator β-catenin provides part of the answer.

PMID:
22361154
DOI:
10.1016/j.cub.2012.01.002
[Indexed for MEDLINE]
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