Send to

Choose Destination
See comment in PubMed Commons below
J Clin Neurosci. 2012 Jun;19(6):903-4. doi: 10.1016/j.jocn.2011.09.015. Epub 2012 Feb 20.

Reversible antecollis associated with pramipexole in a patient with Parkinson's disease.

Author information

  • 1Department of Neurology, Konkuk University Hospital, Seoul, Republic of Korea.


Antecollis is a frequent complication in multiple system atrophy but is rare in Parkinson's disease (PD). We report an 80-year-old patient with a four-year history of PD who developed antecollis six weeks after taking pramipexole (1 mg/day). When assessed in the outpatient clinic, she had antecollis, cogwheel rigidity on the right side, and mild bradykinesia. We found no evidence of myopathic or neurogenic changes in the neck muscles on needle electromyography. We withdrew the pramipexole immediately, and, one week later, her antecollis improved dramatically. This report emphasizes the importance of considering dopamine agonists as a possible cause of antecollis and shows that immediate withdrawal of these drugs may reverse the symptoms.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center