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Ugeskr Laeger. 2012 Feb 20;174(8):480-3.

[Cost of vaccination and cost of sick leave are determinants of cost-effectiveness vaccination against rotavirus].

[Article in Danish]

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  • 1Institut for Sundhedstjenesteforskning, Syddansk Universitet, Denmark.


The literature on cost-effectiveness of oral vaccination against rotavirus infection in high-income European countries is assessed in order to show which parameters are important for evaluation results and recommendations on inclusion in child immunization programs. There is a high degree of variation in results due to variation in country specific incidence rates, unit costs and assumed price of the vaccination. A determining factor is whether only costs to the health care system are included or whether a broader approach to costing is applied. A Danish discussion on this issue is pivotal.

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