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Sensors (Basel). 2011;11(1):1177-91. doi: 10.3390/s110101177. Epub 2011 Jan 20.

Respiratory monitoring by porphyrin modified quartz crystal microbalance sensors.

Author information

1
Graduate School of Environmental Engineering, The University of Kitakyushu, 1-1 Hibikino, Wakamatsu, Kitakyushu 808-0135, Japan. romanselyanchyn@gmail.com

Abstract

A respiratory monitoring system based on a quartz crystal microbalance (QCM) sensor with a functional film was designed and investigated. Porphyrins 5,10,15,20-tetrakis-(4-sulfophenyl)-21H,23H-porphine (TSPP) and 5,10,15,20-tetrakis-(4-sulfophenyl)-21H, 23H-porphine manganese (III) chloride (MnTSPP) used as sensitive elements were assembled with a poly(diallyldimethyl ammonium chloride) (PDDA). Films were deposited on the QCM resonators using layer-by-layer method in order to develop the sensor. The developed system, in which the sensor response reflects lung movements, was able to track human respiration providing respiratory rate (RR) and respiratory pattern (RP). The sensor system was tested on healthy volunteers to compare RPs and calculate RRs. The operation principle of the proposed system is based on the fast adsorption/desorption behavior of water originated from human breath into the sensor films deposited on the QCM electrode.

KEYWORDS:

layer-by layer approach; porphyrin based thin films; quartz crystal microbalance; respiratory monitoring; sensor array

PMID:
22346621
PMCID:
PMC3274104
DOI:
10.3390/s110101177
[Indexed for MEDLINE]
Free PMC Article
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