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Indian J Pharmacol. 2012 Jan;44(1):114-7. doi: 10.4103/0253-7613.91880.

Evaluation of antioxidant activity of two important memory enhancing medicinal plants Baccopa monnieri and Centella asiatica.

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1
Herbal Medicine Division, Defence Institute of Bio-Energy Research (DIBER), DRDO, Field Station, Pithoragarh-262501, Uttarakhand, India.

Abstract

BACKGROUND:

Free radicals or highly reactive oxygen species are capable of inducing oxidative damage to human body. Antioxidants are the compounds which terminate the attack of reactive species and reduce the risk of diseases. Both Baccopa monnieri and Centella asiatica are used in treatment of brain disorders in humans and have almost similar effects.

OBJECTIVE:

The study was conducted to determine the antioxidant properties of two well-known memory enhancer medicinal plants Baccopa monnieri and Centella asiatica.

RESULTS:

The antioxidant activity of these two medicinal plants was evaluated by measuring reducing ability, free radical scavenging activity by DPPH and hydrogen peroxide methods. The antioxidants compounds like ascorbic acid, total phenols and tannins were also evaluated in these plants. Baccopa monnieri and Centella asiatica exhibited significant differences (P<0.05) in their antioxidant values. The methanolic extract of whole leaf powder of Baccopa monnieri exhibited significantly higher antioxidant activity than the Centella asiatica. The antioxidant components viz. ascorbic acid, total phenols and tannins were also found in a higher concentration in Baccopa monnieri as compared to Centella asiatica.

CONCLUSION:

It can be concluded from the study that regular use of Baccopa monnieri as a supplement could be more helpful compared to Centella asiatica in treatment of neurological disorders caused by free radical damage.

KEYWORDS:

Baccopa monnieri; DPPH; antioxidant activity; centella asiatica; free radical scavenging activity; hydrogen peroxide; reducing ability

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