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Clin Perinatol. 2012 Mar;39(1):1-10. doi: 10.1016/j.clp.2011.12.001. Epub 2012 Jan 11.

A quality improvement approach to optimizing medication use in the neonatal intensive care unit.

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1
Clinical Quality Improvement MEDNAX Services/Pediatrix Medical Group/American Anesthesiology, 1301 Concord Terrace, Sunrise, FL 33323, USA. Dan_Ellsbury@pediatrix.com

Abstract

Despite many years of heavy use in premature and critically ill newborns, surprisingly few medications have been rigorously tested in neonatal multicenter randomized clinical trials. Little is known about the pharmacology of these drugs at various birth weights, gestational ages, and chronologic ages. This article describes a quality improvement approach to evaluating and improving neonatal intensive care unit (NICU) medication use, with an emphasis on adaptation of drug use to the specific clinical NICU context and use of system-based changes to minimize harm and maximize clinical benefit.

PMID:
22341532
DOI:
10.1016/j.clp.2011.12.001
[Indexed for MEDLINE]
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