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Nature. 1990 Nov 8;348(6297):137-43.

Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins.

Author information

1
Department of Physiological Chemistry, University of Wisconsin, Madison 53706.

Abstract

By analysis of a temperature-sensitive yeast mutant, a heat-shock protein in the matrix of mitochondria, mitochondrial hsp70 (Ssc1p), is found to be involved both in translocation of nuclear-encoded precursor proteins across the mitochondrial membranes and in (re)folding of imported proteins in the matrix.

PMID:
2234077
DOI:
10.1038/348137a0
[Indexed for MEDLINE]

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