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J Clin Virol. 2012 May;54(1):76-8. doi: 10.1016/j.jcv.2012.01.016. Epub 2012 Feb 14.

First case report of an acute genotype 3 hepatitis E infected pregnant woman living in South-Eastern France.

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Institut National de la Santé et de la Recherche Médicale (INSERM), U895, Nice F-06204, Cedex 3, France.


In European countries, epidemiology of hepatitis E virus (HEV) infection is not well known. Although, seroprevalence of HEV Immunoglobulin G reached a few percent in European women, no acute hepatitis E during pregnancy has been described so far. Here, we report a case of an autochthonous HEV genotype 3 infection in a 41-years-old pregnant woman living in a non-endemic country. The acute hepatitis had a spontaneous good outcome for the mother and the child. In non-endemic areas where Hepatitis E infections are emerging, unexplained cytolysis, whatever its level, in a pregnant woman could be investigated for HEV, using biological molecular and serology tools.

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