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Mol Biol Med. 1990 Aug;7(4):365-9.

Sequence of a cDNA encoding human galactose-1-phosphate uridyl transferase.

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  • 1Department of Pediatrics, Emory University, Atlanta, GA 30322.


We report a revised sequence of a cDNA that encodes a human galactose-1-phosphate uridyl transferase. The cDNA is 1295 bases in length and encodes a 43,000 Mr protein. The sequence was derived from a cDNA clone isolated from a transformed human lymphoblast cell line and amplified in a polymerase chain reaction. The revised sequence reveals a higher degree of amino acid conservation between the human enzyme and the homologous enzymes from Escherichia coli and yeast than was previously thought to exist.

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