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Int J Clin Exp Med. 2012;5(1):92-5. Epub 2012 Jan 15.

Myxofibrosarcoma with metastasis to the lungs, pleura, and mediastinum: a case report and review of literature.

Abstract

Myxofibrosarcoma is a common connective tissue neoplasm of malignant fibrocytes in a myxoid matrix favoring the extremities. Like many other tumors of connective tissue, soft tissue sarcoma exhibits high recurrence rates but is rarely known to metastasize. We present a patient with myxofibrosarcoma of the hand with metastases to the lungs, pleura, and mediastinum. The mediastinal metastasis presented clinically with gastrointestinal symptoms due to compression of the gastroesophageal junction. To our knowledge, this is the first report of metastatic myxofibrosarcoma of the hand and also the first report of metastatic myxofibrosarcoma to mediastinal lymph nodes at the level of the gastroesophageal junction. We also performed a comprehensive literature review of metastatic myxofibrosarcoma.

KEYWORDS:

Myxofibrosarcoma; soft tissue sarcoma

PMID:
22328954
PMCID:
PMC3272692
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