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Mol Cell. 2012 Feb 10;45(3):271-3. doi: 10.1016/j.molcel.2012.01.014.

How to activate a gene: decap its associated noncoding RNA.

Author information

1
Department of Reproductive Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093-0695, USA.

Abstract

Capped and polyadenylated long noncoding RNAs (lncRNAs) are shown to be degraded by a DCP2-mediated turnover mechanism by Geisler et al. (2012); this provides a new level of regulatory control for inducible genes by lncRNAs.

PMID:
22325347
PMCID:
PMC4281020
DOI:
10.1016/j.molcel.2012.01.014
[Indexed for MEDLINE]
Free PMC Article

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