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Nutr J. 2012 Feb 10;11:8. doi: 10.1186/1475-2891-11-8.

Cocoa intake and arterial stiffness in subjects with cardiovascular risk factors.

Author information

1
Primary Care Research Unit, La Alamedilla Health Center, Avda, Comuneros 27, 37003 Salamanca, Spain. donrecio@gmail.com

Abstract

BACKGROUND:

To analyze the relationship of cocoa intake to central and peripheral blood pressure, arterial stiffness, and carotid intima-media thickness in subjects with some cardiovascular risk factor.

FINDINGS:

DESIGN:

A cross-sectional study of 351 subjects (mean age 54.76 years, 62.4% males).

MEASUREMENTS:

Intake of cocoa and other foods using a food frequency questionnaire, central and peripheral (ambulatory and office) blood pressure, central and peripheral augmentation index, pulse wave velocity, ambulatory arterial stiffness index, carotid intima-media thickness, and ankle-brachial index.

RESULTS:

Higher pulse wave velocity and greater cardiovascular risk were found in non-cocoa consumers as compared to high consumers (p < 0.05). In a multivariate analysis, these differences disappeared after adjusting for age, gender, the presence of diabetes, systolic blood pressure and antihypertensive and lipid-lowering drug use. All other arterial stiffness measures (central and peripheral augmentation index, ambulatory arterial stiffness index, ankle-brachial index, and carotid intima-media thickness) showed no differences between the different consumption groups.

CONCLUSIONS:

In subjects with some cardiovascular risk factors, cocoa consumption does not imply improvement in the arterial stiffness values.

TRIAL REGISTRATION:

Clinical Trials.gov Identifier: NCT01325064.

PMID:
22325068
PMCID:
PMC3299654
DOI:
10.1186/1475-2891-11-8
[Indexed for MEDLINE]
Free PMC Article

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