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Immunogenetics. 2012 Jun;64(6):455-60. doi: 10.1007/s00251-012-0599-z. Epub 2012 Feb 10.

Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules.

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1
Centre for Immune Regulation and Department of Immunology, University of Oslo and Oslo University Hospital, Rikshospitalet, Oslo, Norway. l.m.sollid@medisin.uio.no

Abstract

Celiac disease is caused by an abnormal intestinal T-cell response to gluten proteins of wheat, barley and rye. Over the last few years, a number of gluten T-cell epitopes restricted by celiac disease associated HLA-DQ molecules have been characterized. In this work, we give an overview of these epitopes and suggest a comprehensive, new nomenclature.

PMID:
22322673
PMCID:
PMC3349865
DOI:
10.1007/s00251-012-0599-z
[Indexed for MEDLINE]
Free PMC Article
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