Format

Send to

Choose Destination
Development. 2012 Mar;139(5):829-41. doi: 10.1242/dev.060426.

Human pre-implantation embryo development.

Author information

1
Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.

Abstract

Understanding human pre-implantation development has important implications for assisted reproductive technology (ART) and for human embryonic stem cell (hESC)-based therapies. Owing to limited resources, the cellular and molecular mechanisms governing this early stage of human development are poorly understood. Nonetheless, recent advances in non-invasive imaging techniques and molecular and genomic technologies have helped to increase our understanding of this fascinating stage of human development. Here, we summarize what is currently known about human pre-implantation embryo development and highlight how further studies of human pre-implantation embryos can be used to improve ART and to fully harness the potential of hESCs for therapeutic goals.

PMID:
22318624
PMCID:
PMC3274351
DOI:
10.1242/dev.060426
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center