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J Affect Disord. 2012 May;138(3):409-16. doi: 10.1016/j.jad.2012.01.004. Epub 2012 Feb 6.

Effectiveness of six-week psychoeducation program on adherence of patients with bipolar affective disorder.

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Department of Nursing, School of Health Sciences, Duzce University, Duzce, Turkey.



This study examined the effectiveness of a six week psychoeducation program on the adherence of patients with Bipolar Affective Disorder.


An experimental study was conducted at a mood disorder outpatient clinic in Zonguldak, Turkiye. Participants were randomly assigned to either intervention (n=35) or control groups (n=36). Both groups were given pre-tests and post-tests to measure their adherence. In the psychoeducation group, the psychoeducation program was provided for 2 h/week for six weeks. In the control group, standard care and information were provided.


After six weeks, the psychoeducation program significantly improved patients' adherence. The treatment adherence rate of the patients in the intervention group increased from 40.0% (14 patients on pre-test), to 86.7% (26 patients on post-test). Meanwhile, the treatment adherence rate of the control group was 38.9% (14 patients) for the pre-test, and 24.2% (8 patients) for the post-test.


This controlled trial study demonstrated that a six-week psychoeducation program can be a useful intervention to improve adherence in patients undergoing bipolar affective disorder rehabilitation. More comprehensive mental health outcomes need to be undertaken. Further studies exploring a longer term follow-up are also required.

[Indexed for MEDLINE]

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