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Brief Bioinform. 2012 Jul;13(4):420-9. doi: 10.1093/bib/bbr080. Epub 2012 Feb 4.

Measuring the microbiome: perspectives on advances in DNA-based techniques for exploring microbial life.

Author information

1
Department of Biological Sciences, Institute for Bioinformatics and Evolutionary Studies, University of Idaho, Moscow, ID 83844-3051, USA. foster@uidaho.edu

Abstract

This article reviews recent advances in 'microbiome studies': molecular, statistical and graphical techniques to explore and quantify how microbial organisms affect our environments and ourselves given recent increases in sequencing technology. Microbiome studies are moving beyond mere inventories of specific ecosystems to quantifications of community diversity and descriptions of their ecological function. We review the last 24 months of progress in this sort of research, and anticipate where the next 2 years will take us. We hope that bioinformaticians will find this a helpful springboard for new collaborations with microbiologists.

PMID:
22308073
PMCID:
PMC3404397
DOI:
10.1093/bib/bbr080
[Indexed for MEDLINE]
Free PMC Article

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