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Cell Stem Cell. 2012 Feb 3;10(2):113-4. doi: 10.1016/j.stem.2012.01.012.

Engineering stem cell expansion.

Author information

1
Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98109, USA. lbernste@fhcrc.org

Abstract

In this issue of Cell Stem Cell, Csaszar et al. (2012) develop a culture method that overcomes current limitations in ex vivo hematopoietic stem/progenitor cell expansion by continuously diluting inhibitory signaling factors and maintaining stem cell density. This approach enhances the generation of precursors with potential therapeutic utility.

PMID:
22305560
DOI:
10.1016/j.stem.2012.01.012
[Indexed for MEDLINE]
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