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Immunopharmacol Immunotoxicol. 2012 Oct;34(5):779-85. doi: 10.3109/08923973.2012.654610. Epub 2012 Feb 3.

A qualitative description of the peptide sharing between poliovirus and Homo sapiens.

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1
Department of Biochemistry and Molecular Biology, Universityof Bari, Bari, Italy.

Abstract

In a companion paper, we reported that pentapeptides from human poliovirus 1, Mahoney strain, occur repeatedly in human proteins for a total of more than 18,000 overlaps. In the present study, we describe the distribution of the polio pentapeptides throughout biochemical pathways and networks characterizing functions and tissues in the human host. The present study might be of help to better define the poliovirus-host relationships as well as for designing peptide modules with anti-polio activity.

PMID:
22303874
DOI:
10.3109/08923973.2012.654610
[Indexed for MEDLINE]
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