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Antivir Ther. 2012;17(5):933-6. doi: 10.3851/IMP2038. Epub 2012 Feb 1.

Antiviral effect of maraviroc in semen: a case report.

Author information

1
Laboratory of Virology, INSERM U1043, IFB, CHU de Toulouse, Université Paul Sabatier - Toulouse 3, Toulouse, France. pasquier.c@chu-toulouse.fr

Abstract

We describe the antiviral effect of maraviroc in a patient who had been shedding high levels of HIV-1 in seminal fluid for three years despite an undetectable blood plasma viral load. Adding maraviroc to HAART stopped the seminal shedding. We discuss the mechanisms involved and the effect on sexual transmission.

PMID:
22297568
DOI:
10.3851/IMP2038
[Indexed for MEDLINE]

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