Does post-mastectomy radiotherapy represent a contraindication to skin-sparing mastectomy and immediate reconstruction: an update

Surg Oncol. 2012 Jun;21(2):e67-74. doi: 10.1016/j.suronc.2011.12.007. Epub 2012 Jan 30.

Abstract

The use of skin-sparing mastectomy (SSM) to facilitate breast reconstruction is increasing due to a wide acceptance of improved cosmetic outcomes and evidence of equivalence in oncologic outcomes. The rates of patients undergoing mastectomy for whom post-mastectomy radiotherapy (PMRT) will be recommended is increasing as evidence of decreased loco-regional recurrence and increased survival mounts. PMRT may adversely effect complication rates and cosmetic outcomes for patients undergoing immediate breast reconstruction and PMRT--although the evidence for this is methodologically flawed. This article summarises the above evidence and highlights a reconstructive algorithm that may be used to mitigate the possible deleterious effects of PMRT on results.

Publication types

  • Review

MeSH terms

  • Algorithms
  • Breast Neoplasms / radiotherapy
  • Breast Neoplasms / surgery*
  • Contraindications
  • Dermatologic Surgical Procedures*
  • Epidemiologic Methods
  • Female
  • Humans
  • Mammaplasty / methods*
  • Mastectomy / methods*
  • Neoplasm Recurrence, Local / etiology
  • Organ Sparing Treatments / methods*
  • Postoperative Care*
  • Radiotherapy
  • Surgical Flaps
  • Watchful Waiting