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Endocrinology. 2012 Mar;153(3):1049-54. doi: 10.1210/en.2011-1979. Epub 2012 Jan 31.

Minireview: Glucagon in stress and energy homeostasis.

Author information

1
Department of Investigative Medicine, Commonwealth Building, Imperial College London, Hammersmith Campus, Du Cane Road, London W12 0HS, United Kingdom.

Abstract

Glucagon is traditionally thought of as an antihypoglycemic hormone, for example in response to starvation. However, it actually increases energy expenditure and has other actions not in line with protection from hypoglycemia. Furthermore, it is often found to be elevated when glucose is also raised, for example in circumstances of psychological and metabolic stress. These findings seem more in keeping with glucagon having some role as a hormone enhancing the response to stress.

PMID:
22294753
PMCID:
PMC3281544
DOI:
10.1210/en.2011-1979
[Indexed for MEDLINE]
Free PMC Article

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