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Drug Des Devel Ther. 2012;6:1-11. doi: 10.2147/DDDT.S12894. Epub 2011 Dec 22.

Treatment for primary hypothyroidism: current approaches and future possibilities.

Author information

1
Department of Endocrinology, Royal Devon and Exeter Hospital and Peninsula Medical School, Exeter, UK.

Abstract

Primary hypothyroidism is the most common endocrine disease. Although the diagnosis and treatment of hypothyroidism is often considered simple, there are large numbers of people with this condition who are suboptimally treated. Even in those people with hypothyroidism who are biochemically euthyroid on levothyroxine replacement there is a significant proportion who report poorer quality of life. This review explores the historical and current treatment options for hypothyroidism, reasons for and potential solutions to suboptimal treatment, and future possibilities in the treatment of hypothyroidism.

KEYWORDS:

levothyroxine; primary hypothyroidism; thyroid; thyroid-stimulating hormone; triiodothyronine

PMID:
22291465
PMCID:
PMC3267517
DOI:
10.2147/DDDT.S12894
[Indexed for MEDLINE]
Free PMC Article

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