Format

Send to

Choose Destination
J Nat Prod. 2012 Mar 23;75(3):473-8. doi: 10.1021/np200963r. Epub 2012 Jan 30.

An endogenous bile acid and dietary sucrose from skin secretions of alkaloid-sequestering poison frogs.

Author information

1
School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK. frogchemistry@gmail.com

Abstract

The skins of Madagascar poison frogs (Mantella) and certain Neotropical poison frogs (Epipedobates, Dendrobates) secrete the new bile acid tauromantellic acid (1), which was found in both wild-caught and captive-born frogs. This is the first molecule of endogenous origin detected in skin secretions from these taxa. Sucrose was also detected in secretions from wild-caught Mantella but not in captive-born frogs, suggesting a dietary origin.

PMID:
22289087
PMCID:
PMC3311751
DOI:
10.1021/np200963r
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for American Chemical Society Icon for PubMed Central
Loading ...
Support Center