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Rev Med Chil. 2011 Oct;139(10):1286-91. doi: /S0034-98872011001000006. Epub 2012 Jan 3.

[Efficacy and safety of a very-low-calorie diet in a group of overweight or obese Chilean women].

[Article in Spanish]

Author information

1
Departmento de Nutrición Clínica, Clínica Las Condes, Santiago, Chile. acuevas@clc.cl

Abstract

BACKGROUND:

Very low calorie diets (VLCDs) have been used to induce a rapid decrease in total body weight.

AIM:

To evaluate the efficacy and safety of a VLCD in a group of overweight and obese Chilean women.

MATERIAL AND METHODS:

Thirty women with a body mass index (BMI) > 27 kg/m2 were enrolled to a 4 weeks intervention with a VLCD (using liquid meal replacement). Anthropometric and metabolic parameters were evaluated at baseline and at the end of the intervention.

RESULTS:

Twenty five women (83%) completed the total intervention period. Average weight loss was 5.7 ± 1.5 kg (-6.9% of the initial weight) corresponding to a 34.7 ± 13.4% of the excess of weight. Significant improvements in triglycerides, total cholesterol and LDL cholesterol (Low Density Lipoproteins) were observed. Insulin resistance determined by Homeostasis model assessment (HOMA), decreased significantly from 3.3 ± 1.8 to 2.0 ± 0.9 (p = 0.003). No serious adverse events were reported.

CONCLUSIONS:

Short term use of VLCDs is safe and effective to induce rapid weight loss in Chilean women.

PMID:
22286727
DOI:
/S0034-98872011001000006
[Indexed for MEDLINE]
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