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Metab Syndr Relat Disord. 2012 Jun;10(3):181-8. doi: 10.1089/met.2011.0097. Epub 2012 Jan 27.

High prevalence of metabolic syndrome in Iran in comparison with France: what are the components that explain this?

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1
Unité de recherche Génétique Cardiovasculaire EA 4373, Université de Lorraine, Faculté de Pharmacie, Nancy, France.

Abstract

BACKGROUND:

The aim of this study was to investigate the difference in the prevalence of metabolic syndrome and its components between an Iranian and a French population.

METHODS:

The prevalence of metabolic syndrome, defined according to the Adult Treatment Panel III (ATP III), and of related abnormalities, was estimated in 1,386 French and 1,194 Iranian adults.

RESULTS:

The prevalence of metabolic syndrome was significantly higher in Iranian women (55.0%), followed by Iranian men (30.1%), than in French men (13.7%) and French women (6.6%). Iranian women were characterized by high rates of abdominal obesity (65.0%), hypertension (52.1%), hypertriglyceridemia (43.1%), and low high-density lipoprotein cholesterol (HDL-C; 92.7%). Iranian men were characterized by high rates of hypertension (48.9%), hypertriglyceridemia (42.8%), and low HDL-C (81.8%). French men had high rates of hypertension (44.7%) and mild rates of hypertriglyceridemia (28.6%) and hyperglycemia (23.9%). There was a relationship between waist circumference and the lipid components of metabolic syndrome in both countries.

CONCLUSION:

The main finding of this study is the high prevalence of low HDL-C concentrations in the Iranian population, especially in Iranian women, compared with French women. Explanation of this observation could help in establishing prevention strategies.

PMID:
22283632
DOI:
10.1089/met.2011.0097
[Indexed for MEDLINE]

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