Format

Send to

Choose Destination
J Am Chem Soc. 2012 Feb 15;134(6):2852-5. doi: 10.1021/ja2074856. Epub 2012 Jan 31.

Transcription regulation system mediated by mechanical operation of a DNA nanostructure.

Author information

1
Institute for Integrated Cell-Material Sciences, Kyoto University, Yoshida-ushinomiyacho, Sakyo-ku, Kyoto 606-8501, Japan. endo@kuchem.kyoto-u.ac.jp

Abstract

A transcription regulation system initiated by DNA nanostructure changes was designed and constructed. Using the toehold system, specific DNA strands induced the opening of the tubular structure. A transcription product from the purified tube-attached dsDNA template was observed by addition of DNA strands that were specific for opening the tubular structure.

PMID:
22283546
DOI:
10.1021/ja2074856
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for American Chemical Society
Loading ...
Support Center