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Open Rheumatol J. 2011;5:100-6. doi: 10.2174/1874312901105010100. Epub 2011 Dec 30.

The normal synovium.

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Rheumatology Unit, Repatriation General Hospital, Daws Road, Daw Park, South Australia, SA 5041, Australia.


This paper describes the structure and function of the normal synovium including the cellular content, nerve and vascular supply and how normal synovium maintains homeostasis within the joint. It is important to understand normal synovium before appreciating the changes that occur in the synovial membrane which leads to the pathology seen in inflammatory arthritides such as Rheumatoid Arthritis.


Normal synovial membrane; alterations in inflammatory arthritis.; function; nerve supply; structure; vascular supply

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