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Genes Dev. 2012 Jan 15;26(2):105-9. doi: 10.1101/gad.185280.111.

Wnt signaling: the β-cat(enin)'s meow.

Author information

1
Stem Cell Program, Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, California 92093, USA.

Abstract

In a study in the December 15, 2011, issue of Genes & Development, Valenta and colleagues (pp. 2631-2643) constructed a series of β-catenin mutants that allowed them to separate β-catenin's activity as a mediator of Wnt signaling from its activity as cell adhesion component. In doing so, they uncovered some surprising properties of Wnt signaling.

PMID:
22279043
PMCID:
PMC3273833
DOI:
10.1101/gad.185280.111
[Indexed for MEDLINE]
Free PMC Article

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