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J Card Surg. 2012 Mar;27(2):189-91. doi: 10.1111/j.1540-8191.2011.01404.x. Epub 2012 Jan 26.

Aortic valve replacement in patients with systemic mastocytosis.

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  • 1Department of Cardiovascular and Thoracic Surgery, Allegheny General Hospital, Pittsburgh, Pennsylvania 15212, USA.


Systemic mastocytosis is a hematologic disorder with important perioperative implications. A variety of stimuli and medications can cause severe anaphylaxis in these patients. We report successful preoperative, intraoperative, and postoperative management of a patient with systemic mastocytosis who underwent an aortic valve replacement and review the literature pertaining to cardiac surgery in these patients.

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