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Food Chem Toxicol. 2012 Mar;50(3-4):1109-17. doi: 10.1016/j.fct.2012.01.004. Epub 2012 Jan 18.

In vivo UVB-photoprotective activity of extracts from commercial marine macroalgae.

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Department of Pharmacology, University of Alcalá, Alcalá de Henares, and Dermatology Service, Hospital Ramon y Cajal, Madrid, Spain.


The photoprotective potential against UVB radiation of extracts obtained from 21 commercial macroalgae from the Phyla Ochrophyta and Rhodophyta, was evaluated in vivo, using the zebrafish embryo as a whole model organism. Our results showed that the phenolic extracts from Macrocystis pyrifera and Porphyra columbina exhibited the highest photoprotective activity, close to complete photoprotection (100%), similar to that obtained for the carrageenophytes Sarcothalia radula and Gigartina skottsbergii. Under the assayed conditions, the extracts were safe and non-toxic to the embryos at a concentration of 0.04 mg/ml PGE.

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