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Gastroenterology. 1990 Dec;99(6):1705-9.

Excremental studies in human neonates. Identification of zinc coproporphyrin as a marker for meconium.

Author information

1
Department of Pediatrics, University of Wisconsin School of Medicine, Madison.

Abstract

Zinc coproporphyrin, isomers I and III (I:III ratio, approximately 8:1), was identified in human meconium using high-performance liquid chromatography, ultraviolet-visible absorbance spectroscopy, and emission fluorescence spectroscopy. The high levels of zinc coproporphyrin in the first stools of life decrease steadily as meconium is evacuated and reach a plateau at comparatively negligible levels after complete evacuation of meconium. Zinc coproporphyrin can be used as a marker for human meconium.

PMID:
2227283
DOI:
10.1016/0016-5085(90)90476-h
[Indexed for MEDLINE]

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