Send to

Choose Destination
See comment in PubMed Commons below
Conf Proc IEEE Eng Med Biol Soc. 2011;2011:5527-30. doi: 10.1109/IEMBS.2011.6091410.

A time-domain approach for the identification of atrial fibrillation drivers.

Author information

Biosignals and Biophysics Laboratory, Department of Physics and BIOtech, University of Trento, Trento, Italy.


The localization of atrial fibrillation (AF) driver sources, characterized by rapid and regular electrical activity, is crucial for an effective ablation treatment. This work proposes a double-criteria approach for the identification of AF drivers based on a time-domain evaluation of atrial rate and AF organization. These two features are quantified by the measurement of atrial cycle length (ACL) and wave-similarity (WS). Based on ACL/WS formalism, AF drivers can be operatively defined as sites displaying electrical activity with high-rate and high-similarity (HR AND HS). The capability of ACL/WS analysis to identify AF driver sites and distinguish them from non-critical areas is shown in representative examples. The double-criteria evaluation for the identification of AF drivers, provided by our time-domain approach, might open new perspectives for the development of electrogram-guided ablation strategies in the single patient.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for IEEE Engineering in Medicine and Biology Society
    Loading ...
    Support Center