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FEBS J. 2012 Apr;279(8):1355. doi: 10.1111/j.1742-4658.2012.08493.x. Epub 2012 Mar 27.

Quinolinic acid: neurotoxicity.

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Department of Pharmacology, University of New South Wales, Sydney, Australia.

Abstract

This minireview series reviews some of the most recent findings about quinolinic acid's cellular toxicity and its implications in diseases such as HIV associated neurocognitive disorders, depressive disorders and schizophrenia, and finally therapeutic strategies with drugs able to interfere with quinolinic acid production and/or effects.

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