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J Clin Gastroenterol. 2012 Nov-Dec;46(10):859. doi: 10.1097/MCG.0b013e318236f18a.

Agranulocytosis induced by proton pump inhibitors.

Author information

1
Department of Respiratory Medicine, University Hospital of Reims, Reims, France. sdury@chu-reims.fr

Abstract

We report the first published case of agranulocytosis induced by omeprazole and its recurrence with esomeprazole, the S-isomer form of omeprazole. Interestingly, we found an homozygotous mutation of CYP2C19*17, responsible for the metabolism of proton pump inhibitors.

PMID:
22240865
DOI:
10.1097/MCG.0b013e318236f18a
[Indexed for MEDLINE]

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