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Ann Behav Med. 2012 Jun;43(3):299-310. doi: 10.1007/s12160-011-9339-0.

Association between type D personality and prognosis in patients with cardiovascular diseases: a systematic review and meta-analysis.

Author information

1
Faculty of Applied Social Sciences, Leipzig University of Applied Sciences, Germany. grande@fas.htwk-leipzig.de

Abstract

BACKGROUND:

Since 1995, the association of type D personality and mortality in patients with cardiovascular diseases has been increasingly investigated.

PURPOSE:

The aim of this meta-analysis was to integrate conflicting results and to examine possible moderators of this association.

METHODS:

Prospective studies assessing type D personality and hard endpoints were selected and pooled in meta-analyses. Cardiovascular diagnosis, type and quality of adjustment, and publication date were examined in moderator analyses.

RESULTS:

Twelve studies on patients with cardiovascular diseases (N = 5,341) were included. Pooled crude and adjusted effects demonstrated a significant association of type D personality and hard endpoints (odds ratio (OR) of 2.28 (95% CI [1.43-3.62]), adjusted hazard ratio (HR) of 2.24 (95% CI [1.37-3.66])). The OR decreased over time (OR 5.02 to OR 1.54). There was no association in congestive heart failure patients.

CONCLUSIONS:

More recent methodologically sound studies suggest that early type D studies had overestimated the prognostic relevance.

PMID:
22237826
DOI:
10.1007/s12160-011-9339-0
[Indexed for MEDLINE]

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