Format

Send to

Choose Destination
Neuropsychobiology. 2012;65(2):70-5. doi: 10.1159/000329553. Epub 2012 Jan 5.

Failure to replicate influence of GRIK4 and GNB3 polymorphisms on treatment outcome in major depression.

Author information

1
Institute of Psychiatry, University of Bologna, Bologna, Italy. alessandro.serretti @ unibo.it

Abstract

In the present study, we aimed to confirm the previous finding of an association between GRIK4 and GNB3 variants (rs195478 and rs5443) and remission and treatment resistance in major depression, using a multicenter sample of 223 patients. We did not find any supporting evidence for such associations. These conflicting data may result from difficulties in the replication of candidate gene association studies.

PMID:
22222462
DOI:
10.1159/000329553
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for S. Karger AG, Basel, Switzerland
Loading ...
Support Center