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Chem Commun (Camb). 2012 Feb 7;48(12):1760-2. doi: 10.1039/c2cc16812j. Epub 2012 Jan 5.

A polycation-chaperoned in-stem molecular beacon system.

Author information

1
Graduate School of Engineering, Nagoya University, Nagoya 464-8603, Japan. asanuma@mol.nagoya-u.ac.jp

Abstract

In the presence of poly(L-lysine)-graft-dextran, an in-stem molecular beacon involving three perylene-anthraquinone pairs in the stem region had a signal/background ratio of as high as 570. Response speed was also remarkable; equilibrium was attained within 5 minutes after addition of substrate DNA at 20 °C.

PMID:
22218646
DOI:
10.1039/c2cc16812j
[Indexed for MEDLINE]

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