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Nucleus. 2012 Mar 1;3(2):115-7. doi: 10.4161/nucl.19099. Epub 2012 Mar 1.

The liquid drop nature of nucleoli.

Author information

1
Department of Molecular Biosciences and Department of Physics and Astronomy, Northwestern University, Evanston, IL, USA. john-marko@northwestern.edu

Abstract

Nucleoli are prominent subnuclear organelles, and are known to be hubs of ribosome synthesis. A recent study of Brangwynne et al. reports that the nucleoli of Xenopus oocytes display "liquid drop" behavior, suggesting that nucleolar structure may be driven by rather simple physical principles.

PMID:
22198683
PMCID:
PMC3383563
DOI:
10.4161/nucl.19099
[Indexed for MEDLINE]
Free PMC Article

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