Send to

Choose Destination
See comment in PubMed Commons below
Cell. 2011 Dec 23;147(7):1440-1. doi: 10.1016/j.cell.2011.12.001.

Learning to protect your genome on the fly.

Author information

Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.


Piwi-interacting RNAs (piRNAs) help defend host genomes against germline transposons. In this issue of Cell, Khurana et al. show how alterations in the piRNA-encoding loci within a single generation allow a naive fly genome to overcome the initially insurmountable challenge imposed by a newly encountered mobile element.

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science Icon for PubMed Central
    Loading ...
    Support Center