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PLoS One. 2011;6(12):e28824. doi: 10.1371/journal.pone.0028824. Epub 2011 Dec 14.

Analyzing and mapping sweat metabolomics by high-resolution NMR spectroscopy.

Author information

1
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia. kutyshenko@rambler.ru

Abstract

The content of human sweat is studied by high-resolution NMR, and the majority of organic components most often found in sweat of conditionally healthy people are identified. Original and simple tools are designed for sweat sampling from different areas of human body. The minimal surface area needed for sampling is in the range of 50-100 cm(2). On all the surface parts of the human body examined in this work, the main constituents forming a sweat metabolic profile are lactate, glycerol, pyruvate, and serine. The only exception is the sole of the foot (planta pedis), where trace amounts of glycerol are found. An attempt is made to explain the presence of specified metabolites and their possible origin.

PMID:
22194922
PMCID:
PMC3237544
DOI:
10.1371/journal.pone.0028824
[Indexed for MEDLINE]
Free PMC Article

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