Drug taking behaviour(DTES), psychiatric condition(DSM-III-R) and physical health were evaluated in 44 HIV-positive inpatients at a detoxification unit for drug addicts during the period October 1987 to December 1988. The investigation revealed marked psychopathology, especially in terms of personality disorders. The patients were followed up at the end of April 1989. At this time ten patients were abstinent, though all of them remained under care. 26 patients had relapsed to heavy abuse. Four had died. An unfavourable outcome seems to correlate with heavy abuse and poor physical health. We discuss the consequences for existing provisions for treatment, as well as alternative solutions.