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Muscle Nerve. 2012 Jan;45(1):144-6. doi: 10.1002/mus.22239.

Skin biopsy-proven flecainide-induced neuropathy.

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1
Department of Neurology, George Washington University, Washington, DC, USA.

Abstract

Flecainide acetate is a classic Ic antiarrhythmic agent used to treat a variety of cardiac arrhythmias. Non-cardiac side effects usually affect the central nervous system. Few case reports of possible flecainide-induced peripheral neuropathy have been reported. We report this unique case in that flecainide-induced sensory neuropathy was confirmed with skin biopsy, and subsequent improvement of neuropathy was documented with assessment of intraepidermal nerve fiber density in a repeat nerve biopsy.

PMID:
22190323
DOI:
10.1002/mus.22239
[Indexed for MEDLINE]
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