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Brief Funct Genomics. 2012 Jan;11(1):71-85. doi: 10.1093/bfgp/elr039. Epub 2011 Dec 19.

Deep sequencing of small RNAs in plants: applied bioinformatics.

Author information

1
University of Exeter, Exeter EX4 4QD, UK. d.j.studholme@exeter.ac.uk

Abstract

Small RNAs, including microRNA and short-interfering RNAs, play important roles in plants. In recent years, developments in sequencing technology have enabled the large-scale discovery of sRNAs in various cells, tissues and developmental stages and in response to various stresses. This review describes the bioinformatics challenges to analysing these large datasets of short-RNA sequences and some of the solutions to those challenges.

PMID:
22184332
DOI:
10.1093/bfgp/elr039
[Indexed for MEDLINE]

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