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Mult Scler. 2012 Jul;18(7):1050-3. doi: 10.1177/1352458511431730. Epub 2011 Dec 19.

Pencil-thin ependymal enhancement in neuromyelitis optica spectrum disorders.

Author information

1
Department of Radiology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.

Abstract

AQP4 water channels are thought to be the target of autoimmune attack in neuromyelitis optica-spectrum disorders (NMOsd). AQP4 are highly expressed on ventricular ependyma. The objective of this study was to describe a novel pattern of linear, 'pencil-thin' enhancement of ventricular ependyma in NMOsd. We report two NMOsd patients with pencil-thin ependymal enhancement along the frontal and occipital horns of lateral ventricles. Differential diagnosis of ependymal enhancement should include NMOsd alongside with infectious and neoplastic etiologies. Pencil-thin ependymal enhancement may be a helpful radiological marker of NMOsd that can be used to differentiate this condition from multiple sclerosis.

PMID:
22183933
DOI:
10.1177/1352458511431730
[Indexed for MEDLINE]

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