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Ann Oncol. 2011 Dec;22 Suppl 8:viii6-viii18. doi: 10.1093/annonc/mdr472.

Designing early detection programs for ovarian cancer.

Author information

1
Molecular Diagnostics Program, Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N., Seattle, WA 98109, USA. nurban@fhcrc.org

Abstract

Human epididymis protein 4 (HE4) shows promise as a serum marker that complements CA125 in the early detection of epithelial ovarian cancer, either as a first-line screen or as a second-line screen in a multimodal strategy. Incorporation of symptoms in a screening strategy that includes CA125 and HE4 may warrant further research.

PMID:
22180403
PMCID:
PMC3280618
DOI:
10.1093/annonc/mdr472
[Indexed for MEDLINE]
Free PMC Article
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