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Mov Disord. 2012 Mar;27(3):428-31. doi: 10.1002/mds.24044. Epub 2011 Dec 15.

A motor signature of REM sleep behavior disorder.

Author information

1
Sleep Disorders Unit, Pitié-Salpêtrière Hospital, APHP, Paris, France.

Abstract

BACKGROUND:

The purpose of this study was to determine if there was a common pattern in movements during REM sleep behavior disorder (RBD).

METHODS:

We blindly compared video-monitored movements during RBD (n = 136 clips) and wakefulness/arousal (n = 53 clips) in patients with Parkinson's disease (n = 29) and without parkinsonism (idiopathic RBD, n = 31; narcolepsy, n = 5).

RESULTS:

The scorers accurately guessed the sleep/wake stage of 94% of video clips. Compared with wake movements, RBD movements were faster and more often repeated, jerky, and pseudohallucinatory, not self-centered, never associated with tremor, and rarely involved the environment in an appropriate manner. A specific posture of the hand (limp wrist with flexed digits) during grasping movements was evidenced during RBD in 48% of patients, reminiscent of hand-babbling in babies.

CONCLUSIONS:

These characteristics of movements were found in the 3 conditions (Parkinson's disease, idiopathic RBD, and primary narcolepsy), delineating a common motor signature of RBD.

PMID:
22173891
DOI:
10.1002/mds.24044
[Indexed for MEDLINE]

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