Comparison of ropivacaine and lidocaine with epinephrine for infiltration anesthesia in dentistry. A randomized study

Am J Dent. 2011 Oct;24(5):305-9.

Abstract

Purpose: To compare the efficacy of maxillary infiltration anesthesia with 0.5% plain ropivacaine or 2% lidocaine with epinephrine 1:100,000.

Methods: 60 volunteers received 1.8 ml of the anesthetic for infiltration anesthesia of maxillary central and lateral incisors and canine teeth. The onset time and duration of pulp anesthesia were assessed with an electric pulp tester. The duration time of numbness of the upper lip was also monitored. Blood pressure and heart rate were measured before and after administration of the solution.

Results: The efficacy of anesthesia of the lateral and central incisors was 100% for both anesthetics. There were small insignificant differences in effectiveness of canine pulp anesthesia. The mean onset time was significantly shorter for ropivacaine--2.2 minutes vs. 5.1 for lidocaine. Ropivacaine also had a significantly longer duration of action--mean time 79.2 minutes. Ropivacaine caused statistically significant increases in blood pressure and heart rate.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Amides / administration & dosage*
  • Anesthesia, Dental / methods*
  • Anesthesia, Local*
  • Anesthetics, Local / administration & dosage*
  • Blood Pressure / drug effects
  • Dental Pulp Test
  • Double-Blind Method
  • Epinephrine / administration & dosage
  • Female
  • Heart Rate / drug effects
  • Humans
  • Lidocaine / administration & dosage*
  • Male
  • Ropivacaine
  • Time Factors
  • Vasoconstrictor Agents / administration & dosage
  • Young Adult

Substances

  • Amides
  • Anesthetics, Local
  • Vasoconstrictor Agents
  • Ropivacaine
  • Lidocaine
  • Epinephrine